摘要
该文回顾中药煮散的历史源流和形成原因,对比分析现代中药配方颗粒的时代背景和未来发展趋势,为中药配方颗粒应用推广提供参考依据.通过查阅历代医学典籍,系统回顾中药煮散的萌芽期、形成期、成熟期及过渡期的状况,全面分析中药煮散在宋代成熟的六大因素.收集国内外现代配方颗粒的研究文献,详细了解其发展历程,客观分析其临床应用现状.将中药煮散与现代配方颗粒的应用特点进行分析对比.①宋代煮散盛行的原因有六大因素:国家实行仁政,广泛提供免费医药;学医、业医者人数大增;军队庞大,用药极费;宋代人口迅速增加;瘟疫频发,疾病增多;中央及地方政府财力不足.②中药配方颗粒的临床应用特点:中药配方颗粒提取并浓缩了中药饮片有效成分,保证疗效同时,补充了现代人群对中药汤剂“速、简、便”的需求且性价比相对较高,但其自身品种限制、质量控制缺乏统一标准、以及单味提取的配方颗粒无法达到配伍中药煎煮过程中的增效、减毒等因素,也制约着其临床应用和推广.③二者在临床应用过程中各有所长,应辨证施治.该文认为中药配方颗粒吸取传统中药煮散“难、繁、浑、乱”的经验教训,解决“呆、贵、限、乱、失”等的问题,是其推广的重要依据.
Abstract
In this study,the origin and causes of cooked traditional Chinese medicine powder were reviewed,and a comprehensive analysis was made for the time background of modern traditional Chinese medicine formula granules and the future development trend,in order to provide reference for application and promotion of traditional Chinese medicine formula granules.By reference to ancient medical books of previous dynasties,a system review was conducted for infancy,formation,maturity and transition of cooked traditional Chinese medicine powder,and a comprehensive analysis was made for the six factors of cooked traditional Chinese medicine powder's maturity in the Song Dynasty.Efforts were made to collect domestic and foreign research literatures of modern formula granules,understand the detailed development,and conduct an objective analysis of the current clinical application of modern formula granules.According to the comparative analysis for the application characteristics of cooked traditional Chinese medicine powder and modern formula granules,①the popularity of cooked traditional Chinese medicine powder in the Song Dynasty has six factors:soaring numbers of medical students and medical practitioners,high medical expenses due to huge army,rapid population growth,frequent epidemics and increasing diseases,and insufficient finances of central and local governments.②On the basis of clinical application characteristics of traditional Chinese medicine formula granules,traditional Chinese medicine formula granules contain extracted and concentrated effective components,which guarantee the curative effect,meet modem people's demands for "quick,simple and convenience" traditional Chinese medicine decoctions,show a relatively high cost performance;however,formula granules are restricted by their varieties and lack unified quality control standards,and single-extract formula granules have not synergy and attenuation effects of combined traditional Chinese medicine decoctions,which also restricts its clinical application and promotion.③Both have advantages in the process of clinical application,and shall be used based on syndromes.In conclusion,traditional Chinese medicine formula granules do not have disadvantages of "difficult,complicated,turbid and disorderly" cooked traditional Chinese medicine powder,and solve such problems as "inflexibility,expensiveness,restriction,disorder and inefficacy",which is the important basis for promoting traditional Chinese medicine formula granules.
基金项目
国家中医药管理局中医药标准化项目(ZYYS-201414)