首页|鞣花鞣质肠道代谢产物urolithins研究进展

鞣花鞣质肠道代谢产物urolithins研究进展

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鞣花鞣质是一类具有诸多生物活性的酚类化合物,近年来研究发现其发挥作用的物质基础与其肠道菌群代谢产物——尿石素密切相关.该研究就近几年国内外关于尿石素的结构特征、类型、分布,以及其改善前列腺、乳腺、结肠相关疾病,抗癌、抗氧化、抗炎等生物活性研究进行了综述,为开发和利用尿石素奠定基础.
Research progress of ellagitannin intestinal metabolite urolithins
Ellagitannins is a kind of phenolic compounds with many biological activities.Recent studies have found that the effective ingredients of these compounds have close relationship with their colon-derived bacteria metabolites,that is urolithins.The objective of this study was to review the structure characteristics,types and distribution of urolithins,improvement in diseases related to prostate,breast and colon,as well as anti-cancer,anti-oxidation,anti-inflammation and other biological activities.The present review will lay the foundation for development and utilization of urolithins.

urolithinsmetabolitedistributionbiological activity

周本宏、邱振鹏、易慧兰、周丁山、汪静、吴玥

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武汉大学人民医院,湖北武汉430060

湖北中医药大学中药资源与中药复方教育部重点实验室,湖北武汉430065

尿石素 代谢产物 分布 生物活性

国家自然科学基金

31570349

2016

中国中药杂志
中国药学会

中国中药杂志

CSTPCDCSCD北大核心
影响因子:1.718
ISSN:1001-5302
年,卷(期):2016.41(16)
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