Traditional Chinese medicines target neutrophil extracellular traps to treat diseases:a review
Neutrophil extracellular traps(NETs)are fibrous networks formed by neutrophils after a procedure called NETosis,with the function of capturing and killing pathogens.NETs are widely involved in the pathological processes of major diseases such as im-mune system diseases,respiratory diseases,metabolic diseases,cancers,and reperfusion injury.Therefore,regulating NETs has be-come one of the important ways to prevent and treat the above diseases.As an excellent traditional culture in China,traditional Chinese medicine has made outstanding contributions to the treatment of diseases.In recent years,studies have discovered that a variety of ac-tive components in traditional Chinese medicines,Chinese medicine compound prescriptions,and single traditional Chinese medicines can alleviate the symptoms by regulating NETs in the pathological process of major diseases.This article reviews the research progress in the regulation of NETs by the active components of traditional Chinese medicines,Chinese medicine compound prescriptions,and single traditional Chinese medicines in the last five years,aiming to serve as a reference for related research.
neutrophil extracellular trapsactive components of traditional Chinese medicinesmechanismresearch progress
NETL
NSTL
万方数据
维普
