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中药临方制剂智能制造的研究实践与发展方向

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近年来,随着人们生活水平不断提高、生活节奏大幅加快,患者对中药学服务的需求和质量不断提高.临方制剂作为中成药、汤药、配方颗粒等现有中药制剂应用形式的重要补充,市场需求越来越大.当前临方制剂主要以手工生产、半机械化生产为主,生产过程控制整体水平不高,数字化和信息化程度低,制约着临方制剂的自动化、智能化发展.研发临方制剂的核心技术和智能设备,推进临方制剂与智能制造相融合,是临方制剂面临的重大发展机遇与挑战.该文概述了智能制造的内涵与特点,总结了"物联网""大数据""人工智能"等智能制造技术在中药行业中的应用概况,并基于"中药物料智能分类-处方和工艺智能决策-在线控制与智能生产"中药临方制剂创新研发模式,介绍了研究团队在中药临方智能制造领域的研究实践与成果,提出了中药临方智能制造的发展方向,为中药临方制剂的自动化、智能化研究与应用提供指导.
Research practice and development direction of intelligent manufacturing of presonalized traditional Chinese medicine preparations
In recent years,as people's living standards continue to improve,and the pace of life accelerates dramatically,the demand and quality of traditional Chinese medicine(TCM)services from patients continue to rise.As an essential supplement to the existing forms of TCM application,such as Chinese patent medicine,decoction,and formulated granules,presonalized TCM preparations is facing an increasing market demand.Currently,manual and semi-mechanized production are the primary production ways in presonalized TCM preparations.However,the production process control level is low,and digitalization and informatization need to be improved,which restricts the automated and intelligent development of presonalized TCM preparations.Presonalized TCM preparations faces a significant opportunity and challenge in integrating with intelligent manufacturing through research and development of intelligent equipment and core technology.This paper overviews the connotation and characteristics of intelligent manufacturing and summarizes the application of intelligent manufacturing technologies such as"Internet of things""big data",and"artificial intelligence"in the TCM industry.Based on the innovative research and development model of"intelligent classification of TCM materials,intelligent decision making of prescription and process,and online control and intelligent production"of presonalized TCM preparations,the research practice and achievements from our research group in the field of intelligent manufacturing of presonalized TCM preparations are introduced.Ultimately,the paper proposes the direction for developing intelligent manufacturing of presonalized TCM preparations,which will provide a reference for the research and application of automation and intelligence of presonalized TCM preparations.

presonalized traditional Chinese medicine preparationsintelligent manufacturingonline controlequipment develop-ment

田文秀、李文杰、薛爱乐、郑敏悦、沈岚、洪燕龙

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上海中医药大学上海中医健康服务协同创新中心,上海 201203

中药现代制剂技术教育部工程研究中心,上海 201203

上海中医药大学中药学院,上海 201203

中药临方制剂 智能制造 在线控制 设备研发

国家自然科学基金上海市"科技创新行动计划"技术标准项目上海中医药慢性病防治与健康服务省部共建协同创新中心项目上海市自然科学基金面上项目

8197349020DZ22009002021科技02-3723ZR1463500

2024

10.19540/j.cnki.cjcmm.20231127.301

中国中药杂志
中国药学会

中国中药杂志

CSTPCD北大核心
影响因子：1.718
ISSN：1001-5302
年,卷(期)：2024.49(3)
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