Two new benzoyl-sesquiterpenes from Mesona chinensis
Mesona chinensis is a common medicinal and edible plant in the Lingnan region of China,which has extensive pharmacological activity.However,the study of its chemical constituents is not sufficient.In this study,a variety of modern chromatographic separation techniques were used to isolate two compounds from 95％ethanol extract of the grass parts of M.chinensis.Their absolute configurations were determined by ultraviolet spectroscopy(UV),infrared spectroscopy(IR),high resolution mass spectrometry(HR-ESI-MS),1D and 2D nuclear magnetic resonance(1D NMR and 2D NMR),and single-crystal X-ray diffraction(SC-XRD).Specifically,they were two new benzoyl-sesquiterpenes and named mesonanol A and mesonanol B,respectively.The results of the pharmacological activity evaluation showed that neither of the two new compounds showed obvious antiviral and anti-inflammatory activities.
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