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中医证候疗效评价方法的研究进展

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中医证候疗效是中医特有且最能体现中医药优势的疗效评价指标。证候疗效评价方法的构建和测量工具的研发,为中医药临床疗效评价与中药新药研发提供客观、量化的证据,是中医药疗效评价创新方法与技术的探索方向。传统中医证候疗效评价的内涵局限于症状、体征的改善,主观因素较强,统一的科学评价标准难以形成,评价方法缺乏统一性和客观性,缺少定量研究。证候疗效的科学内涵、评价思路与方法、关键技术尚不明确,导致中医证候疗效评价模式与方法多样,评价指标各不相同。量表法为中医证候的客观量化和标准化研究提供新思路,成为中医证候疗效评价的重要方法和载体。该文对中医证候疗效评价方法和存在的问题进行系统总结,梳理了中医证候疗效评价量表的研究现状,提出对证候疗效特色与临床价值综合评价的思考,以期为证候疗效评价研究带来更多启示。
Methods for traditional Chinese medicine syndrome-based efficacy evaluation:a review
Traditional Chinese medicine(TCM)syndrome-based efficacy is an evaluation index which is unique to TCM and can reflect the advantages of TCM.The development of the methods and measurement tools for evaluating TCM syndrome-based efficacy can provide objective and quantitative evidence for the clinical efficacy evaluation of TCM and the development of new Chinese medicine preparations,being the exploration direction of innovative methods and technologies for evaluating TCM efficacy.The conventional evaluation methods are subjective and limited to the mitigation of symptoms and the improvement of physical signs,which make it difficult to form a unified evaluation standard.In addition,the evaluation methods lack unity,objectivity,and quantitative research.The scientific connotation,evaluation ideas and methods,and key technologies of the evaluation for the therapeutic effect on syndromes remain unclear,which leads to diverse evaluation modes,methods,and indexes.The syndrome-based efficacy scale provides a new idea for the objective quantification and standardization of TCM syndromes.This review systematically summarizes the methods and problems,introduces the research progress in the evaluation scales,and puts forward some thoughts on the characteristics of TCM syndrome-based efficacy evaluation,aiming to provide insights for the research in this field.

traditional Chinese medicine syndromeefficacy evaluationscale

王建新、任毅铭、丰雪、吕行、史琪、郭曼萍、孙明月、高蕊

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中国中医科学院 西苑医院, 北京 100091

中国中医科学院 博士后流动站, 北京 100700

国家药品监督管理局中药临床研究与评价重点实验室, 北京 100091

北京中医药大学, 北京 100105

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中医证候 疗效评价 量表

中华中医药学会中国中医科学院科技创新工程重大攻关项目

20230145-B2-CACMCI2021A04701

2024

中国中药杂志
中国药学会

中国中药杂志

CSTPCD北大核心
影响因子:1.718
ISSN:1001-5302
年,卷(期):2024.49(6)
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