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人参上市药品研究进展

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人参被誉为"百草之王",是一种重要的药用植物,其药用部位包括根、茎叶、花和果实,以根部最为常用.人参的主要活性成分包括三萜皂苷、多糖和多肽及挥发油等,人参化学成分及其活性代谢物赋予其多种药理作用,应用于治疗疾病和发挥保健功能.人参作为传统中药资源,现已有多种人参制剂获得药品注册并上市,包括人参片、人参口服液、人参注射液等,在调节免疫功能、辅助治疗肿瘤、抗疲劳、延缓衰老、改善糖脂代谢、治疗心血管疾病及抗炎镇痛各方面展现出良好的临床疗效,相关药品的生产工艺和质量标准对保证其药效具有重要意义.该文基于人参"大补元气,补脾益肺,生津止渴、安神益智"的理论指导,较为系统地总结了药用植物人参及源于人参的相关上市药品的临床应用进展,同时关注人参上市药品及相关制品的再开发,为进一步挖掘人参的药用价值和保健功能提供参考.综述以上内容,作为深度开发人参及人参相关上市药的重要基础,为拓展人参的应用提供更多可能性.
Research progress in preparations of Panax ginseng
Panax ginseng,known as the"king of herbs",is a highly valued medicinal plant,and its medicinal parts include roots,stems,leaves,flowers,and fruits,among which the roots are the most commonly used.The main active components of this medicinal plant include triterpenoid saponins,polysaccharides,peptides,and volatile oils.The chemical components and active metabolites en-dow this herb with a variety of pharmacological effects,and thus this herb is used to treat various diseases and play healthcare roles.Currently,a wide range of preparations of P.ginseng have been officially registered and marketed,including tablets,oral liquids,and injections,which demonstrate good clinical efficacy in regulating immunity,adjuvant treatment of tumors,alleviating fatigue,delaying the aging process,improving glucose and lipid metabolism,treating cardiovascular diseases,and relieving inflammation and pain.The production process and quality standards of these drugs are of great significance to ensure their efficacy.According to the theory that Ginseng Radix et Rhizoma can greatly replenish original Qi,tonify the spleen and lung,promote fluid production to quench thirst,tran-quilize mind and enrich the intelligence,this paper systematically summarized the clinical application progress of P.ginseng and rela-ted preparations on the market and prospected the further development of preparations from P.ginseng,providing a reference for further exploring the medicinal value and healthcare function of this herb.The above contents,as an important basis for the in-depth develop-ment of P.ginseng and related drugs,increase the possibilities for the application of P.ginseng.

Panax ginsengmarketed drugsclinical applicationresearch progresspotential value

覃思意、赖嘉敏、贾彬、王乐琪、李莎莎、严诗楷、肖雪

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广东药科大学广东省代谢病中西医结合研究中心(中医药研究所),广东广州 510006

国家药品监督管理局药品快速检验技术重点实验室(广东省药品检验所),广东广州 510663

广州中医药大学第二附属医院,广东广州 510120

上海交通大学药学院,上海 200240

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人参 上市药品 临床应用 研究进展 潜在价值

广州市科技计划项目珠江科技新星专项国家药品监督管理局药品快速检验技术重点实验室开放课题国家药品监督管理局药品快速检验技术重点实验室开放课题

201610010113KF2022002KF2022006

2024

中国中药杂志
中国药学会

中国中药杂志

CSTPCD北大核心
影响因子:1.718
ISSN:1001-5302
年,卷(期):2024.49(7)
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