首页|补肾促卵冲剂治疗高泌乳素血症导致排卵障碍性不孕的临床研究

补肾促卵冲剂治疗高泌乳素血症导致排卵障碍性不孕的临床研究

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研究补肾促卵冲剂治疗高泌乳素血症导致不孕症的治疗作用及安全性。选择60例肾虚血瘀型高泌乳素血症导致不孕症患者，分为试验组(补肾促卵冲剂+甲磺酸溴隐亭片安慰剂)和对照组(甲磺酸溴隐亭片+补肾促卵冲剂安慰剂)，观察排卵率、妊娠率、血清性激素、基础体温(BBT)及中医证候积分。结果显示，试验组临床有效率90。00％，对照组临床有效率80。00％;试验组能够显著降低泌乳素(PRL)水平、增加妊娠率，在增加BBT双相比例、改善中医证候积分、提高排卵率方面优于对照组。结果表明，补肾促卵冲剂治疗高泌乳素血症导致排卵障碍性不孕症疗效确切，安全可靠。
Clinical study of Bushen Culuan Formula in treatment of ovulatory disorder infertility caused by hyperprolactinemia
This paper aims to study the therapeutic effect and safety of Bushen Culuan Formula in the treatment of patients with infertility caused by hyperprolactinemia.Sixty patients with infertility caused by hyperprolactinemia of kidney deficiency and blood stasis were divided into the treatment group(Bushen Culuan Formula+Bromocriptine Mesylate Tablets placebo)and the control group(Bromocriptine Mesylate Tablets+Bushen Culuan Formula placebo),and ovulation rate,pregnancy rate,serum sex hormones,basal body temperature(BBT),and traditional Chinese medicine(TCM)symptom scores were observed.The results showed the clinical effective rate was 90.00％in the treatment group and 80.00％in the control group.The treatment group was able to significantly reduce the PRL level and increase the pregnancy rate,and it was superior to the control group in increasing the BBT biphasic ratio,improving the TCM symptom scores,and enhancing the ovulation rate.The results show that Bushen Culuan Formula is safe and reliable in treating ovulatory disorder infertility caused by hyperprolactinemia,with remarkable effects.

hyperprolactinemiainfertilityovulatory disorder infertilityBushen Culuan Formula

马堃、李佳妮、刘晓倩

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中国中医科学院西苑医院,北京 100091

中华中医药学会,北京 100029

高泌乳素血症 不孕症 排卵障碍性不孕 补肾促卵冲剂

中医药传承与创新"百千万"人才工程(岐黄工程)岐黄学者专项北京市科技计划"首都特色"重点项目首都临床特色应用研究与成果推广项目中国民族医药学会科研项目北京市自然科学基金中国中医科学院科技创新工程项目北京市中医药"薪火传承3+3工程"项目

201826Z1711000010171042021Z2072-3405037212193CI2021A024062017-SZ-B-36

2024

10.19540/j.cnki.cjcmm.20240115.501

中国中药杂志
中国药学会

中国中药杂志

CSTPCD北大核心
影响因子：1.718
ISSN：1001-5302
年,卷(期)：2024.49(8)
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