摘要
胆木是一种药用价值较高的中药材,含有生物碱类、五环三萜及其皂苷类、有机酚酸及其苷类、环烯醚萜类、黄酮类等多种类型化学成分,具有抗病毒、抗菌、解热镇痛、抗炎、免疫调节等作用.该文对胆木已报道的化学成分和药理作用进行系统性综述,并根据质量标志物的概念,从植物亲缘性、化学成分特有性、传统药性药效、化学成分可测性、入血成分及不同产地和采收时期几方面对胆木的质量标志物进行预测分析,以期为胆木的质量评价研究提供依据.
Abstract
Nauclea officinalis is a Chinese medicinal material with a high medicinal value,which contains various chemical constituents such as alkaloids,pentacyclic triterpenoids and their saponins,organic phenolic acids and their glycosides,iridoids,and flavonoids.It has antiviral,antibacterial,antipyretic,analgesic,anti-inflammatory,and immunoregulatory functions.This article systematically reviewed the reported chemical constituents and pharmacological effects of N.officinalis.According to the concept of quality markers,the quality markers of N.officinalis were predicted and analyzed from the aspects of plant kinship,specificity of chemical constituents,traditional drug efficacy,measurability of chemical constituents,plasma components,and different producing areas and harvest times,in order to provide a basis for the quality evaluation of N.officinalis.
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