Research progress on bioactive constituents and pharmacological effects of Tibetan medicine Sinopodophylli Fructus
Sinopodophylli Fructus is a traditional medicine used by the Tibetan people.It is known for its ability to regulate men-struation and promote blood circulation.Presently,bioactive constituents that have been isolated and identified from Sinopodophylli Fructus mainly include 15 lignans(e.g.,podophyllotoxin,deoxypodophyllotoxin,and 4'-demethylpodophyllotoxin)and 20 flavonoids(e.g.,quercetin,kaempferol,and rutin).These components exhibit pharmacological effects such as anticancer,antibacterial,and lipid-lowering activities.Additionally,Sinopodophylli Fructus contains other components such as proteins,fatty acids,polysaccha-rides,vitamins,amino acids,and trace elements.According to the relevant literature reports in China and abroad,this article re-viewed the chemical constituents and pharmacological effects of Sinopodophylli Fructus,aiming to provide references for the develop-ment and rational clinical application of this medicinal resource.
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