摘要
在我国,商陆属植物商陆Phytolacca acinosa或垂序商陆P.americana的干燥根被列为中药商陆.商陆属植物含有三萜类、三萜皂苷类、多糖类、抗病毒蛋白类、黄酮类等多种化学成分,其中最主要的是三萜类及三萜皂苷类化合物.商陆属植物具有抗炎、抗肿瘤、抗细菌、抗真菌、抗疟、驱虫等活性.该文对近年来商陆属植物的化学成分、药理作用、毒性及重金属富集特性进行了归纳整理,以期为商陆属植物的活性成分研究和药物开发提供理论依据.
Abstract
In China,the dry roots of Phytolacca acinosa or P.americana in the Phytolacca plants are listed as the traditional Chinese medicine(TCM)Phytolaccae Radix.Phytolacca plants contain triterpenoids,triterpenoid saponins,polysaccharides,antiviral proteins,flavonoids,and other chemical components.The most important compounds are triterpenoids and triterpenoid saponins.Phytolacca plants have anti-inflammatory,anti-tumor,antibacterial,antifungal,antimalarial,deworming,and other activities.In this paper,the chemical constituents,pharmacological effects,toxicity,and heavy metal enrichment characteristics of Phytolacca plants were summarized to provide a theoretical basis for the study of active ingredients and drug development of Phytolacca plants.