The main chemical constituents from Acori Tatarinowii Rhizoma were isolated and purified using the macroporous resin,microporous resin(MCI)and octadecylsilyl silica gel(ODS)column chromatography,as well as semi-preparative high performance liquid chromatography.Their chemical structures were elucidated by spectroscopic analyses including mass spectrometry(MS),nuclear magnetic resonance(NMR),ultraviolet(UV),infrared(IR)and circular dichoism(CD)combined with literature data.A total of 11 compounds were isolated and identified,including 4 lignan glycosides,2 benzyl alcohol glycosides,4 flavonoid glycosides,and 1 α-tetralone glycoside:(7S,8R)-dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucopyranosyl-9'-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside(1),(7S,8R)-dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucopyranoside(2),(7S,8R)-dihydrodehydrodiconiferyl alcohol di-9,9'-O-β-D-glucopyranoside(3),(+)-lyoniresinol 3α-O-β-D-glucopyranoside(4),benzyl alcohol O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside(5),benzyl alcohol O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside(6),3'-O-methylepicatechin 7-O-β-D-glucopyranoside(7),3'-O-methylcatechin 7-O-β-D-glucopyranoside(8),apigenin 6-C-β-D-glucopyranosyl-7-O-β-D-glucopyranoside(9),isoscoparin 7-O-β-D-glucopyranoside(10),and(4R)-8-hydroxy-α-tetralone-4-O-β-D-glucopyranoside(11).Compound 1 is a new neolignan glycoside,and compounds 2-5 and 7-11 are isolated from genus Acorus for the first time.
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