The secondary metabolites of the endophytic fungus Talaromyces malicola hosted in the arthropod Armadillidium vulgare were separated by silica gel column chromatography,gel column chromatography,and semi-preparative high-performance liquid chromatography.Eleven compounds(1-11)were obtained from the ethyl acetate fraction of the fermentation broth of T.malicola,and their structures were identified by NMR,HR-ESI-MS,UV,IR,and ECD.The 11 compounds were talarosesquiterpene A(1),(3β,5α,6α,15α,22E)-5,6-epoxyergosta-8(14),22-diene-3,7,15-triol(2),vermistatin(3),hydroxyvermistatin(4),bercheminol A(5),penicillide(6),lunatinin(7),penipurdin A(8),emodin(9),BE-25327(10),and(-)-regiolone(11).Compound 1 was a new diaporol-type sesquiterpene.Compounds 2,4-5,and 7-11 were isolated from Talaromyces for the first time.
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