Research progress and prediction of quality markers of Menispermi Rhizoma
Menispermi Rhizoma,the dried rhizome of Menispermum dauricum,has anti-tumor,anti-inflammatory,anti-arrhythmic,anti-myocardial ischemia,and anti-cerebral ischemia activities.The primary constituents of this herbal medicine include alkaloids,pol-ysaccharides,and fatty oils.This study predicts and evaluates the quality markers(Q-markers)of Menispermi Rhizoma by considering the phylogenetic relationship of the plant,chemical composition,conventional effects,component measurability,blood constituents,and network pharmacology.The primary Q-markers of Menispermi Rhizoma are predicted to include daurisoline,dauricine,dauricu-mine,bianfugecine,epiberberine,tetrandrine,acutumidine,6-O-demethylmenisporphine,and acutuminine.The findings hold poten-tial for enhancing the quality evaluation system of Menispermi Rhizoma.
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