Expert consensus on clinical application of Xiangshao Granules
Xiangshao Granules are widely used in clinical practice for the treatment of premenstrual tension syndrome and menopausal syndrome.However,at present,there is no evidence-based medicine guideline or consensus formed.In order to standardize the rational use of drugs by clinical physicians and maximize the value of Xiangshao Granules,this consensus is formulated.The consensus is guided by clinical problems and follows the principle of"evidence-based medicine as the mainstay,consensus as the supplement",objectively evaluating the evidence of Xiangshao Granules in diagnosing and treating diseases,and forming it after full discussion by experts.The consensus was jointly completed by multidisciplinary experts from 29 national tertiary Grade A hospitals and 3 provincial traditional Chinese medicine(TCM)hospitals and universities,including 16 TCM experts,13 western medicine experts,2 integrated TCM and western medicine experts,1 chief pharmacist of TCM,and 2 evidence-based medicine experts.The project was proposed in August 2021 by the China Association of Chinese Medicine(202108050-GS-CACM),and the preparation process lasted for 2 years and was issued on 29 November 2023(GS/CACM 334-2023).This article elaborated on the background of the consensus,explained the preparation process including project initiation,consensus issue construction,formation of recommendations and consensus suggestions,drafting,formation of expert consensus,and solicitation of opinions,clarifying key issues such as the indications,dosage regimen and timing,dosage,course of treatment,safety,and precautions of Xiangshao Granules in clinical application,in order to guide clinicians in standardized and rational drug use.