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芍药甘草汤在消化系统疾病中的应用及其作用机制研究进展

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芍药甘草汤(Shaoyao Gancao Decoction,SGD)是2018年国家中医药管理局公布的《古代经典名方目录(第一批)》中所载方剂之一,由白芍和炙甘草组成.实验及临床案例证明,芍药甘草汤具有抗炎、镇痛、解痉、保肝等功效,现广泛应用于治疗临床疾病,其中在消化系统疾病的治疗中效果良好.该文对近年来有关芍药甘草汤的文献进行整理分析,从基础方证探析、临床应用、作用机制3个方面总结芍药甘草汤在治疗消化系统疾病中的应用,全面阐述了芍药甘草汤在治疗消化系统疾病中的研究现状,并针对目前研究提出了不足之处与改进方法,以期为芍药甘草汤在消化系统疾病的应用以及芍药甘草汤复方制剂研发提供一定的参考意见和借鉴意义.
Shaoyao Gancao Decoction in digestive system diseases:applications and mechanisms
Shaoyao Gancao Decoction (SGD) is one of the prescriptions included in the Catalogue of Ancient Classical Prescriptions (First Batch) published by the National Administration of Traditional Chinese Medicine in 2018.It is composed of Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle.Experiments and clinical cases have proved that SGD has anti-inflammatory,pain-relieving,antispasmodic,and liver-protecting effects.It is widely used in the clinical treatment of diseases,demonstrating definite effects on digestive system diseases.By reviewing the literature on SGD in recent years,this paper summarizes the applications of SGD in the treatment of digestive system diseases from three aspects of basic prescription and syndrome analysis,clinical application,and mechanism to expounds the research status in this field.Furthermore,this paper put forward the shortcomings and improvement methods of the available studies,aiming to provide reference for the application of SGD in treating digestive system diseases and the research and development of SGD preparations.

Shaoyao Gancao Decoctiondigestive system diseasesmechanismclinical applicationreview

丁子涵、王楠、杨骏、李玲、张彤

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上海中医药大学中药学院,上海 201203

上海市黄浦区香山中医医院药剂科,上海 200020

上海中医药大学经方与现代中药融合创新全国重点实验室,上海 201203

芍药甘草汤 消化系统疾病 作用机制 临床应用 综述

2024

中国中药杂志
中国药学会

中国中药杂志

CSTPCD北大核心
影响因子:1.718
ISSN:1001-5302
年,卷(期):2024.49(23)