Current Research in the Mechanism and Clinical Application about Remote Ischemic Preconditioning in Cerebral Infarction
Cerebral infarction is one of the diseases with high rates of disability and death worldwide,but there is still a lack of more effective treatments.Many studies showed that remote ischemic preconditioning(RIPC)can significantly improve ischemic tolerance of target organs,reduce infarct size and improve prognosis.However,its role and mechanism in the development of cerebral infarction are still little studied.This paper will summarize the role and mechanism of RIPC in cerebral infarction from the following aspects:neural,humoral,immune and related signaling pathways,and review the current research progress of RIPC in clinical cerebral ischemic diseases to provide a reference for subsequent research.