Obesity-Related Chronic Inflammation and Cerebro-Metabolic Disease
Cerebrovascular disease has become the second cause of death worldwide,and its risk is mainly attributed to metabolic disorders.This paper reviewed the pathogenesis of obesity-related chronic inflammation and cerebro-metabolic disease.The aggregation of immune cells,heightened secretion of pro-inflammatory factors and vascular endothelial injury are important pathogenic mechanisms of cerebro-metabolic disease in obesity state.New and effective prevention and treatment strategies such as lifestyle intervention,drug immunotherapy and weight reduction anti-inflammatory therapy targeting inflammation are expected to provide reference for reducing the incidence of cerebro-metabolic diseases while enhancing both patient survival rates and quality of life.
万方数据
维普
