Application of Metabolomics in Cerebro-Metabolic Disease
Cerebrovascular diseases are the leading cause of death and disability worldwide.A high proportion of cerebrovascular diseases is correlated with metabolism disorder.Cerebro-metabolic disease refers to a clinical syndrome with cerebrovascular injury caused by traditional metabolic risk factors and residual metabolic risk factors,vascular structural injury and dysfunction as the main pathophysiological manifestations,and intervention of metabolic risk factors can effectively improve the prognosis.Metabolomics is a scientific method that uses high-throughput omics technology to identify and quantify all metabolites,which is an important starting point for future research on cerebro-metabolic disease.This paper summarizes the studies of metabolomics and lipidomics in cerebro-metabolic disease and cardiometabolic disease,aiming to provide references for the development of metabolomics studies and clinical prevention and treatment of cerebro-metabolic disease.