Relationship between Visual Impairment and Cognitive Function in Elderly Patients with Post-Stroke Mild Cognitive Impairment
Objective To investigate the correlation between visual impairment and cognitive function in elderly patients with post-stroke mild cognitive impairment(PSMCI).Methods Patients with acute ischemic stroke admitted to Chongqing University Three Gorges Hospital from February 2020 to February 2022 were prospectively and continuously included.MMSE and MoCA were used to evaluate the cognitive function of the patients,and binocular visual acuity,eye movement,visual field,visual perception and visual attention were measured.According to the occurrence of PSMCI at 6 months follow-up,the patients were divided into PSMCI group and non-PSMCI group.Clinical data were collected and the risk factors of PSMCI in patients with acute ischemic stroke were analyzed by multivariate logistic regression.Results A total of 157 patients were included,of which 71 cases(45.22％)developed PSMCI,108 cases(68.79％)developed visual impairment,of which 58 cases(53.70％)had central visual impairment,30 cases(27.78％)had visual field loss,41 cases(37.96％)had abnormal eye movement,and 30 cases(27.78％)had visual perception deficit.The total incidence of visual impairment,the incidence of central visual impairment,abnormal eye movement,visual field loss and visual perception deficit in the PSMCI group were higher than those in the non-PSMCI group(P<0.05),the age was higher than that in the non-PSMCI group(P<0.05).The difference was statistically significant.Older age,(OR1.919,95％CI1.310-2.813,P<0.001)higher NIHSS score(OR2.291,95％CI1.423-3.689,P<0.001),large infarction(OR1.669,95％CI1.203-2.315,P<0.001)and visual impairment(OR1.998,95％CI1.363-2.928,P<0.001)were risk factors for PSMCI in patients with acute ischemic stroke(all P<0.05).Conclusions Visual impairment is associated with PSMCI in patients with acute ischemic stroke.Visual impairment may aggravate cognitive impairment.
万方数据
维普
