A Case Report of Capsule Warning Syndrome Treated with Tirofiban Bridging Dual Antiplatelet Therapy after Intravenous Thrombolysis with Alteplase
Capsule warning syndrome(CWS)is a group of rare clinical symptoms with frequent episodes of stereotyped neurological deficits,and easy progression to complete stroke.This study reported a case of CWS with paroxysmal speech inarticulateness and left limb weakness.Within 24 hours after intravenous thrombolysis with alteplase,the patient still had repeated episodes of stereotypical speech inarticulateness and left limb weakness.After assessing the risk,tirofiban was given within 24 hours after intravenous thrombolysis,and dual antiplatelet therapy was bridged 3 days later.The patient had no recurrence of neurological deficits.However,the timing of initiation of dual antiplatelet therapy after intravenous thrombolysis and the dual antiplatelet therapy program still need large-scale data to further explore.