Paroxysmal Nocturnal Hemoglobinuria with Posterior Reversible Encephalopathy Syndrome:A Case Report
Posterior reversible encephalopathy syndrome(PRES)is a clinical-imaging syndrome dominated by reversible neurological damage and specific imaging manifestations,and paroxysmal nocturnal hemoglobinuria(PNH)is a clinically rare disease.This paper described a case of an elderly male patient with PNH who had long-term chronic hemolytic anemia.After irregularly taking low-dose immunosuppressants and short-term intermittent infusion of 10 U of washed erythrocytes,he developed a PRES with headache,seizures,mental behavioural abnormalities,abnormally high blood pressure,and trace subarachnoid hemorrhage.It should be differentiated from diseases such as cerebral venous and venous sinus thrombosis and reversible cerebral vasoconstriction syndrome.The aim of this paper is to improve the clinicians'ability to prevent and identify this type of patients at an early stage.