Research Progress on the Potential Role of Taurine in Cerebro-Metabolic Disease and its Mechanism
The concept of cerebro-metabolic disease,which centers on cerebrovascular damage caused by metabolic risk factors,has been proposed and is in the early stages of exploration.The prevention and treatment of cerebro-metabolic disease focus on the control of metabolic risk factors.At present,the clinical drug strategy is still based on the individual intervention of each metabolic risk factor,which brings a lot of trouble to patients due to the variety of drugs used and the high dosage.Therefore,there is an urgent need for a synergistic drug with multiple targets to reduce the drug burden and improve the efficacy in patients with cerebro-metabolic disease.Taurine,as a conditionally essential amino acid,has a variety of biological effects such as regulation of glycolipid metabolism,osmotic pressure regulation,cell membrane stabilization,antioxidation,anti-aging,etc.,which has potential clinical value for cerebro-metabolic disease treatment.This paper focused on the pleiotropy of taurine and discussed the mechanism of taurine in cerebro-metabolic disease and its clinical application prospects.
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维普
