Research Progress on Factors Related to the Susceptibility Vessel Sign and its Clinical Application in Acute Ischemic Stroke
Intravenous thrombolysis and endovascular treatment in the treatment time window can reduce the mortality and disability rate of patients with acute ischemic stroke(AIS),which is the level Ⅰa evidence recommended by the national guidelines for AIS,but may cause revascularization failure and more serious complications.Susceptibility vessel sign(SVS)is defined as the presence of hypointensity in the area of the responsible vessel on T2 WI or SWI scans.The SVS reflects the hemosiderin content and is highly sensitive to thrombus.Therefore,SVS can be used to infer the subtype of AIS,the thrombus burden,the symptom onset time,and other factors associated with successful revascularization.It is helpful to guide the selection of treatment for hyperacute ischemic stroke,assess the efficacy of treatment,and reduce the occurrence of poor prognosis.The clinical application of SVS has been controversial because there are many factors affecting it.This paper reviewed the influencing factors,such as the symptom onset time,stroke subtype,thrombus location,MRI scanner,and the clinical application of SVS.