Dosimetric analysis of dynamic intensity modulated radiotherapy with active breathing coordinator and Catalyst for respiratory gating after breast conserving surgery for left breast cancer
Objective To compare the dosimetric differences between active breathing coordinator(ABC)and Catalyst for respiratory gating after breast conserving surgery for left breast cancer.Methods Data of 48 female patients with left breast cancer after breast conserving surgery admitted to the Radiotherapy Department of Shenzhen People's Hospital from November 2020 to August 2021 were retrospectively selected.They were randomized to receive dynamic intensity modulated radiotherapy(IMRT)plans with ABC or Catalyst.The dosimetric differences in targets and organs at risk between the two groups were analyzed.Results Comparison of the two respiratory gating IMRT plans revealed no statistically significant differences(P＞0.05)in D90％,D98％,Dmax,Dmean,conformity index(CI),homogeneity index(HI),and monitor unit parameters in the target volume,(i.e.,chest wall),as well as the ipsilateral lung and heart under the deep inhalation breath hold(DIBH)mode.The Dmean,Dmax,and D2％of the left anterior descending coronary artery(LAD)in the Catalyst group were better than those in the ABC group[(1 047.72±1 401.84)vs.(454.48±206.26),(1 619.28±809.05)vs.(1 068.53±419.63),(1 405.85±798.30)vs.(1 016.54±592.00)cGy],with statistically significant differences(t=-2.07,-3.18,-2.07,P＜0.05).Conclusions Both ABC and Catalyst respiratory gating systems meet the requirements for clinical treatment,with the latter more effective in reducing the exposure dose of LAD.
Deep inspiration breath holdRespiratory gatingIntensity modulated radiotherapyBreast conserving surgery
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