肺癌患者接受放疗和免疫治疗后引发治疗相关性肺炎的研究进展
Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy
王猷嘉 1韩光1
作者信息
- 1. 华中科技大学同济医学院附属湖北省肿瘤医院放疗中心,武汉 430000
- 折叠
摘要
放射治疗和免疫治疗作为当下癌症治疗的重要组成部分,带来治疗效果的同时也伴随着不良反应的发生.胸部恶性肿瘤患者接受放疗联合免疫治疗后,生存率及生活质量没有达到预期的高度,其中一项主要原因就是治疗相关性肺炎的发生.为了更深入地了解放疗联合免疫治疗肺癌所导致的肺炎,在此对其发病机制、发病情况与危险因素、鉴别诊断与治疗作一综述.
Abstract
Radiotherapy and immunotherapy prove significant for cancer treatment presently.Despite therapeutic effects,they carry risks of adverse reactions.The survival rates and quality of life of patients with thoracic malignancies frequently fail to fulfill expectations after they receive radiotherapy combined with immunotherapy.A major reason for this is the occurrence of treatment-associated pneumonitis.To gain a deeper understanding of the pneumonitis induced by radiotherapy combined with immunotherapy for lung cancer,this paper reviews the pathogenesis,incidence,risk factors,differential diagnosis,and treatment of such pneumonitis.
关键词
肺癌/放射治疗/免疫检查点抑制剂/放射-免疫相关性肺炎Key words
Lung cancer/Radiotherapy/Immune checkpoint inhibitor/Radiation-induced immune-related pneumonitis引用本文复制引用
基金项目
中华国际医学交流基金中青年医学研究专项(Z-2014-06-2102)
武汉市知识创新专项(2022)(2022020801010512)
出版年
2024
NETL
NSTL
万方数据