FLASH radiotherapy(FLASH-RT)has garnered considerable attention globally in recent years.Compared to conventional radiotherapy,FLASH-RT can deliver the total radiation dose to the target volume in an extremely short time,reducing the radiation-induced damage to normal tissue while maintaining similar anti-tumor effects.FLASH-RT has been in the clinical trial stage,with several clinical research result being reported.Based on the collected global clinical research result of FLASH-RT in recent years,this study systematically reviewed FLASH-RT's safety,radiation-related side effects,treatment efficacy,opportunities,and challenges in clinical trials.
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