Objective To study the prognosis of congenital bile duct cysts following cyst resection,and to analyze the risk factors associated with the development of postoperative biliary calculus.Methods Clinical data of 149 patients with congenital bile duct cysts undergoing surgery in the First Affiliated Hospital of Nanjing Medical University from May 2004 to January 2022 were retrospectively analyzed,including 59 males and 90 females,with a median age of 32(21,47)years old.Patients were divided into two groups:the stone group(n=51,biliary calculus occurred during the follow-ups after surgery)and non-stone group(n=98).Clinical data such as gender,age,medical history,cyst type,biliary calculus,anastomotic ste-nosis and occurrence of cancer were compared.All patients were followed up via telephone consultations.A logistic regression analysis was used to identify the risk factors associated with the occurrence of biliary calcu-lus after surgery.Results The duration of the follow-ups was 120(24,211)months.The observed incidence of postoperative biliary calculus,anastomotic stricture,and cancer in the patients were 34.2％(51/149),8.7％(13/149),and 4.7％(7/149),respectively.The logistic regression analysis indicated that incomplete cyst resection(OR=3.332,95％CI:1.221-9.094)and postoperative anastomotic steno-sis(OR=13.300,95％CI:2.586-68.401)were associated with a higher risk of biliary calculus forma-tion after cystectomy(all P＜0.05).Conclusion Patients with congenital bile duct cysts suffer a high risk of biliary calculus formation after cystectomy.The residual cyst and postoperative anastomotic stenosis are independent risk factors for biliary calculus after surgery.
Bile ductsCongenital bile duct cystsGallstonePostoperative complicationMalignancy
NETL
NSTL
万方数据
