急性胆石性胰腺炎病因学的研究进展
Research progress in etiology of acute gallstone pancreatitis
张雅男 1王奥 2张莉 3郭贤德 2李宁1
作者信息
- 1. 天津大学中西医结合医院肝胆胰外科,天津 300100
- 2. 天津医科大学南开临床学院,天津 300100
- 3. 天津大学中西医结合医院内镜中心,天津 300100
- 折叠
摘要
急性胆石性胰腺炎(AGP)是一种由胆结石引起的急性胰腺炎,其病因学复杂,解剖基础和始动因素对发病具有协同作用,需要共同研究.胆胰管汇合方式、扩张的主胰管、相对狭小的乳头开口以及小结石或微小结石可能共同参与了 AGP的发病过程,其中小结石最为重要.对AGP应做到病因诊断和临床治疗同步进行,针对不同病因及时选择相应的治疗方式能最大程度上缓解患者病情并降低治疗成本.目前AGP的预测指标难以统一,发病过程和相关防治方法有待研究.本文就AGP发病的解剖基础、始动因素、发病机理及自身防御等方面进行综述,为治疗提供参考.
Abstract
Acute gallstone pancreatitis(AGP)is a kind of acute pancreatitis caused by gallstones.The etiology of AGP is complex,and the anatomic basis and initiating factors have a synergistic effect on its pathogenesis,which needs to be studied jointly.The way of the confluence of pancreaticobiliary ducts,dilated main pancreatic duct,the relatively narrow opening of duodenal papilla and small stones or microlithiasis may be involved in the pathogenesis of AGP,in which small stones are the most important.Etiological diag-nosis and clinical treatment of AGP should be carried out simultaneously.The timely selection of treatment methods for different causes can alleviate the patient's condition to the greatest extent and reduce the cost of treatment.At present,it is difficult to unify the prediction indexes of AGP.Meanwhile,the pathogenesis and related prophylaxis and treatment also need to be studied.In this paper,the anatomic basis,initiation factors,pathogenesis and self-defense of AGP were analyzed to provide a new perspective for its treatment.
关键词
胰腺炎/胆结石/病因学Key words
Pancreatitis/Gallstone/Etiology引用本文复制引用
基金项目
天津市自然科学基金重点项目(21JCZDJC00550)
出版年
2024
NETL
NSTL
万方数据