Oddi括约肌功能障碍动物模型的研究进展
Advances in animal models of sphincter of Oddi dysfunction
林豪男 1梁易璇 2赵王强 2曹君葳 2王天麒 1梁卓睿 2王长淼1
作者信息
- 1. 大连医科大学附属第一医院普外三科,大连 116000
- 2. 大连医科大学中西医结合学院,大连 116000
- 折叠
摘要
Oddi括约肌功能障碍(SOD)是指Oddi括约肌生理功能异常,可引发胆道、胰腺和肝脏等的一系列疾病.目前SOD的相关研究正成为热点,但是其发病机制并不明确,本文将综述国内外关于SOD的文献,分析不同实验动物模型的优劣势,并对药物和手术造模特点进行分析,为今后相关模型建立提供参考.
Abstract
Sphincter of Oddi dysfunction(SOD)refers to the abnormal physiological function of sphincter of Oddi,which causes a series of syndromes in biliary tract,pancreas and liver.At present,the related research of SOD is becoming a hot spot,but its pathogenesis is not clear.This article will review the domestic and international literatures on SOD,review the advantages and disadvantages of experimental ani-mals such as rabbits,dogs and guinea pigs,and analyze the characteristics of drugs and surgical modeling,so as to provide references for future related model establishment.
关键词
奥狄括约肌功能障碍/动物/模型/综述Key words
Sphincter of Oddi dysfunction/Animal/Model/Review引用本文复制引用
出版年
2024
NETL
NSTL
万方数据