The liver is a solid organ with excellent regenerative potential.Its regenerative ability is closely related to liver disease.In-depth study of the mechanism of liver regeneration is of great significance for understanding liver biology and developing regenerative medicine.The mouse has been the most widely used animal model of liver regeneration for its technical,economic and anatomical advantages.The current mouse models of liver regeneration include partial liver resection,chemical drug injury,and genetic engi-neering models.In this review,we compared their advantages,shortcomings and application prospects to provide reference for future research.
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