Objective To analyze the effect of mucosal ligament preservation on the outcome of arthroscopic repair of me-niscus injury.Methods A total of 77 patients with knee meniscus tears caused by sports injuries who underwent arthroscopic me-niscus repair or suture in Zhengzhou Orthopaedic Hospital from June 2022 to June 2023,were retrospectively analyzed.Including 45 males and 32 females,aged 38.57±13.54 years(range,52-87 years),body mass index 24.72±4.01 kg/m2(range,34.14-13.61 kg/m2).All patients complained of knee pain,limited activity and walking weakness.The symptoms were not relieved after 1 month of conservative treatment,which seriously affected daily work and life.According to the intraoperative treatment of mucosal liga-ment,the patients were divided into mucosal ligament preservation group and mucosal ligament removal group.The visual ana-logue score(VAS),Lysholm score,and total blood loss were compared between the two groups.Results All patients successfully completed the operation and were followed up for an average of 5.23±2.16 months(range,3-9 months).The operation time was 47.59±16.81 min in mucosal ligament preservation group and 45.25±15.93 min in mucosal ligament removal group,and there was no significant difference between the two groups(t=0.628,P=0.532).The total blood loss in the mucosal ligament preservation group was 246±193 ml,which was less than 343±211 ml in the mucosal ligament removal group,and the difference was statistical-ly significant(t=2.095,P=0.040).None of the patients received allogeneic blood transfusion.The hematocrit of the mucosal liga-ment preservation group was 42.48%±4.57%before operation and 39.42%±4.65%on the third day after operation,while that of the mucosal ligament removal group was 41.24%±4.16%and 38.95%±3.80%.The difference between the two groups was statisti-cally significant(t=0.016,P=0.004;t=0.004,P=0.016).There was no significant difference between the two groups before opera-tion and on the third day after operation(t=0.217,P=0.545;t=0.629,P=0.159).The preoperative VAS score of mucosal ligament preservation group was 7.25±1.10,which was higher than that of 3 months after operation(0.83±1.06),and the difference was sta-tistically significant(t=0.062,P<0.001).The preoperative VAS score of mucosal ligament removal group was 7.16±1.21,which was higher than that of 3 months after operation(1.05±1.13),and the difference was statistically significant(t=0.017,P<0.001).There was no significant difference in VAS scores between the two groups before operation and at 3 months after operation(t=0.144,P=0.740;t=0.273,P=0.603).The preoperative Lysholm score of mucosal ligament preservation group was 31.76±7.54,which was significantly lower than that of 3 months after operation 87.30±4.12(t=-39.329,P<0.001);The Lysholm score of the mucosal ligament removal group was 34.13±7.32 before operation,which was lower than 89.05±4.45 at 3 months after operation,and the difference was statistically significant(t=-40.172,P<0.001);There was no significant difference in Lysholm score between the two groups before operation and 3 months after operation(t=1.395,P=0.167;t=1.766,P=0.081).Conclusion The preserva-tion of mucosal ligament in arthroscopic surgery for meniscus injury does not prolong the operation time.It can reduce the total in-traoperative blood loss,and the postoperative knee function recovery is similar to that of mucosal ligament removal.