成人普遍筛查HBV感染和接种乙型肝炎疫苗,加速消除乙型肝炎
Universal HBV screening and vaccination for adults to accelerate elimination of hepatitis B
庄辉1
作者信息
- 1. 北京大学医学部基础医学院病原生物学系暨感染病中心,北京 100191
- 折叠
摘要
慢性乙型肝炎病毒(HBV)感染可导致肝硬化、肝衰竭、肝细胞癌和其他肝病相关死亡.虽然现行抗病毒治疗不能彻底治愈慢性乙型肝炎,但早期治疗、长期随访和肝癌监测可减少慢性肝病的发病率和相关肝病死亡率.对成人普遍筛查HBV 3项标志物是降低慢性乙型肝炎发病率和相关肝病死亡率的关键措施(一生中至少检测1次).此外,成人普遍接种乙型肝炎疫苗可保护易感人群免受HBV感染.成人HBV普遍筛查和乙型肝炎疫苗接种,是实现世界卫生组织提出的2030年消除病毒性肝炎公共卫生危害的关键措施.
Abstract
Chronic hepatitis B virus(HBV)infection can lead to cirrhosis,hepatic failure,hepatocellular carcinoma and other liver-related death.Although current antiviral therapies cannot completely cure chronic hepatitis B,early-stage treatment,long-term follow-up,and liver cancer monitoring can reduce the morbidity of chronic liver disease and related liver disease mortality.Universal screening of adults for triple-panel HBV markers(at least once in a lifetime)is a key step to reduce the incidence rate of chronic hepatitis B and related liver disease mortality.In addition,universal HBV vaccination for adults can protect a susceptible population from HBV infection.Universal screening of adults for HBV and hepatitis B vaccination are key measures to achieve the World Health Organization's proposal of eliminating the public health threat of viral hepatitis by 2030.
关键词
乙型肝炎/普遍筛查/疫苗接种/消除/预防Key words
Hepatitis B/Universal screening/Vaccination/Elimination/Prevention引用本文复制引用
出版年
2024
NETL
NSTL
万方数据