Objective:To evaluate the application value of precise laparoscopic hepatectomy under the concept of enhanced recovery after surgery (ERAS) in the treatment of hepatic hemangioma.Methods:60 patients with hepatic hemangioma who underwent precise laparoscopic hepatectomy in Hunan Provincial People's Hospital from April 1, 2018 to April 1, 2022 were recruited. The informed consents of all patients were obtained and the local ethical committee approval was received. Among them, 24 patients were male and 26 female, aged from 33 to 71 years, with a median age of 42 years. 30 patients who were diagnosed and treated after 2020 were assigned into the ERAS group, and 30 cases before 2020 were allocated into the control group. Perioperative conditions were observed between two groups. The data, such as length of postoperative hospital stay, were compared between two groups by t test, and the rate comparison, such as surgical method, was performed by Chi-square test.Results:Patients in both groups completed the surgery successfully, without conversion to open surgery. In the ERAS group, 2 patients underwent left hepatectomy, 9 cases of right hepatectomy and 19 cases segmental hepatectomy, and 5, 9 and 16 cases in the control group, correspondingly, where no significant difference was observed between two groups (χ2=1.543, P>0.05). No postoperative complications, such as bleeding, liver failure and bile leakage, occurred in two groups. No perioperative death or readmission at postoperative 90 d was reported in two groups. In the ERAS group, the visual analogue scale (VAS) score at postoperative 24 h, time to first flatus and defecation, drainage tube indwelling time, length of hospital stay and hospitalization expense were 3.7±0.6, (29±7) h, (43±8) h, (22±5) h, (5.3±1.2) d and (5.4±1.0)×104 Yuan, significantly less compared with 4.1±0.7, (36±7) h, (53±8) h, (40±7) h, (6.5±1.5) d and (6.1±1.1)×104 Yuan in the control group (t=-2.382, -4.034, -4.823, -11.945, -3.305, -2.362; P<0.05).Conclusions:Precise laparoscopic hepatectomy under the ERAS concept is a safe and effective treatment for hepatic hemangioma, which can accelerate rapid recovery, shorten the length of hospital stay and reduce hospitalization expenses.