Study on the operation stability of a new type domestic electro-pneumatic ventilator in hyperbaric oxygen chamber
王丛 1薛连璧 2于秋红 1刘亚玲 1任梓齐 1刘影 1张寓景
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作者信息
1. 首都医科大学附属北京天坛医院高压氧科，北京 100070
2. 华中科技大学协和深圳医院高压氧科，深圳 518052
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摘要
目的 探讨国产新型高压氧（HBO）专用电控气动呼吸机在高气压环境中以压力控制模式（PCV）运行时的稳定性。 方法 将呼吸机气动部分与模拟肺连接安装于舱内，呼吸机电控部分与模拟肺数据采集电脑置于舱外，在PCV模式下根据预设吸气压力（PI）分5个预设水平（1.0、1.5、2.0、2.5、3.0 kPa），按舱内压力分为0.10 MPa组、0.15 MPa组、0.20 MPa组，采集气道峰压（Ppeak）、潮气量（VT）和分钟通气量（MV）；每组20个循环，比较各预设PI在3组中的参数的变化。 结果 随环境压力升高，各组预设PI中Ppeak、VT、MV均出现下降，差异均有统计学意义（均P<0.05），下降幅度<6%。 结论 国产高压氧专用电控气动呼吸机在HBO舱内（0.10～0.20 MPa）以PCV运行时随着舱内压力升高呼吸参数出现差异，但该变化在临床使用相对稳定范围内。 Objective To investigate the operation stability of a new type domestic electro-pneumatic ventilator during pressure-controlled ventilation（PCV）in hyperbaric oxygen（HBO）chamber. Methods The pneumatic part of the HBO ventilator and a test lung were connected and placed inside a hyperbaric chamber. The electric part of the ventilator was placed outside the chamber along with a computer connected with the test lung for real-time data collection. During the PCV，the inspiratory pressures（PI）were preset at five levels（1.0，1.5，2.0，2.5，and 3.0 kPa），under three different chamber pressures（0.10 MPa，0.15 MPa，and 0.20 MPa），respectively. The peak inspiratory pressure（Ppeak），the tide volume（VT），and the minute volume（MV）as displayed by the ventilator and the test lung were recorded at each level of PI for 20 cycles. The differences of the three groups of data were then compared and analyzed. Results As the chamber pressure increased，the Ppeak，VT，and the MV at each level of PI decreased within a narrow range（<6%），and the differences were statistically significant（P<0.05）. Conclusion When the HBO electro-pneumatic ventilator working in PCV mode in a HBO chamber（0.10–0.20 MPa），its ventilation indexes can have some changes as the pressure increasing，but the changes are still within the relative stable range for clinical application.
Abstract
Objective To investigate the operation stability of a new type domestic electro-pneumatic ventilator during pressure-controlled ventilation（PCV）in hyperbaric oxygen（HBO）chamber. Methods The pneumatic part of the HBO ventilator and a test lung were connected and placed inside a hyperbaric chamber. The electric part of the ventilator was placed outside the chamber along with a computer connected with the test lung for real-time data collection. During the PCV，the inspiratory pressures（PI）were preset at five levels（1.0，1.5，2.0，2.5，and 3.0 kPa），under three different chamber pressures（0.10 MPa，0.15 MPa，and 0.20 MPa），respectively. The peak inspiratory pressure（Ppeak），the tide volume（VT），and the minute volume（MV）as displayed by the ventilator and the test lung were recorded at each level of PI for 20 cycles. The differences of the three groups of data were then compared and analyzed. Results As the chamber pressure increased，the Ppeak，VT，and the MV at each level of PI decreased within a narrow range（<6%），and the differences were statistically significant（P<0.05）. Conclusion When the HBO electro-pneumatic ventilator working in PCV mode in a HBO chamber（0.10–0.20 MPa），its ventilation indexes can have some changes as the pressure increasing，but the changes are still within the relative stable range for clinical application.
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