Objective To observe the impact of seasickness on metabolism.Methods A total of 35 servicemen aboard a naval ship were divided into seasickness group and non-seasickness group during a long voyage.The urea,creatinine,uric acid,alanine transaminase,alkaline phosphatase,total bilirubin,direct bilirubin,hydroxybutyrate dehydrogenase,lactic dehydrogenase,and amylase in the serum were detected on the first day and forth day after entering the rough sea,and the changes were compared and analyzed.Results On the first day after entering the rough sea,the urea[(6.81±1.09)mmol/L vs.(5.85±0.83)mmol/L],creatinine[(85.38±10.53)μmol/L vs.(77.85±6.50)μmol/L],and uric acid[(447.85±51.88)μmol/L vs.(381.00±50.69)μmol/L]in the seasickness group were significantly higher than those in the non-seasickness group(P＜0.05);in the seasickness group,the urea,creatinine,and uric acid[(5.99±1.30)mmol/L vs.(6.81±1.09)mmol/L、(78.15±11.89)mmol/L vs.(85.38±10.53)mmol/L,(358.38±77.70)μmol/L vs.(447.85±51.88)μmol/L]on the fourth day were significantly lower than those on the first day(P＜0.01),while the alanine transaminase and alkaline phosphatase on the fourth day were significantly lower than those on the first day.There was no significant difference in total bilirubin,direct bilirubin,hydroxybutyrate dehydrogenase,lactic dehydrogenase,and amylase between the seasickness group and the non-seasickness group on the first day after entering the rough sea.Conclusion Seasickness can significantly impact metabolic indicators of the body.Upon the onset of seasickness,the serum urea,creatinine,and uric acid significantly increased,but significantly decreased three days later.There was no significant change of alanine transaminase and alkaline phosphatase at the onset of seasickness,but these indicators decreased significantly after three days.Serum urea and uric acid are the main indicators of the impact of seasickness on metabolism;and seasickness has no significant effect on serum bilirubin,hydroxybutyrate dehydrogenase,lactic dehydrogenase,and amylase.
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