Effects of hyperbaric oxygen therapy on neurological function,fibrinogen,and fasting blood glucose of stroke patients
Objective To investigate the effects of hyperbaric oxygen(HBO)therapy on neurological function,fibrinogen,and fasting blood glucose of stroke patients.Methods A total of 66 stroke patients admitted to Shenshan Medical Center of Memorial Hospital of Sun Yat-sen University from September 2022 to June 2023 were prospectively selected as research subjects and divided into an HBO group(n=40)and a conventional treatment group(n=26).The National Institutes of Health stroke scale(NIHSS),basic activities of daily living(BADL),and levels of fibrinogen and fasting blood glucose were compared before and after treatment within each group as well as between groups.Results Compared with those before treatment,both groups exhibited significant reductions in NIHSS scores[(7.68±6.64)points,(5.35±3.91)points vs.(6.03±4.71)points,(4.92±3.54)points]and notable increases in BADL[(43.75±28.03)points,(56.54±24.85)points vs.(60.88±24.98)points,(58.65±26.37)points]scores after treatment.In the HBO group,there were marked decreases in fibrinogen and fasting blood glucose levels[(3.73±1.15)g/L,(6.19±2.01)mmol/L vs.(3.08±0.97)g/L,(5.28±0.85)mmol/L]all with statistically significant differences(P＜0.05 orP＜0.01).Furthermore,after treatment,when the HBO group was compared with the conventional treatment group,the improvements in NIHSS and BADL scores,as well as the reduction in fibrinogen levels,were more obvious,all with statistically significant differences(P＜0.05 or P＜0.01).Conclusion HBO can promote the recovery of neurological function in stroke patients,improve the ability to perform activities of daily living,and ameliorate the levels of fibrinogen and fasting blood glucose.
StrokeNational Institutes of Health stroke scaleBasic activities of daily livingFibrinogenBlood glucoseHyperbaric oxygen therapy
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