Objective To investigate whether the image quality of total-body PET/CT(TB PET/CT)with 1 min acquisition can meet the clinical diagnostic requirements.Methods From May 2019 to September 2021,a total of 90 malignant tumor patients(60 males,30 females,age 31-86 years)with pri-mary lesions confirmed by pathological diagnosis in Zhongshan Hospital,Fudan University were respectively analyzed.All patients underwent conventional PET/CT(C PET/CT)scan with conventional clinical acqui-sition and TB PET/CT scan with 1 min acquisition after injecting 18F-FDG in random order.Paired t test or Wilcoxon signed rank test was used to analyze the image quality of these two scans.Results SUVmax of pri-mary lesions in TB PET/CT group was significantly higher than that in C PET/CT group(15.9(7.9,24.6)vs 12.5(5.8,16.6);z=8.14,P＜0.001),so were signal-to-noise ratio(SNR)of the blood pool,liver,mus-cles(9.3±3.0,11.4(9.5,14.2),8.3(7.3,10.1)vs6.2±1.7,9.4(7.7,11.8),6.0(4.9,7.1)),tumor-to-blood pool ratio(TBR)(9.3(4.3,14.8)vs 8.5(4.3,11.1)),tumor-to-liver ratio(TLR)(6.7(3.0,10.4)vs 6.1(2.9,7.7)),tumor-to-muscle ratio(TMR)(23.2(11.5,38.0)vs 18.3(9.6,26.6);t=9.36,z values:4.44-7.40,all P＜0.001).Conclusion The image quality of TB PET/CT scan with 1 min acquisition can meet the diagnostic requirements,and is better than the C PET/CT image quality with conventional clinical acquisition.
NETL
NSTL
维普
万方数据
