全身PET/CT 1 min采集图像与常规PET/CT图像质量比较:自身对照研究
Comparison of the image quality between total-body PET/CT with 1 min acquisition and conven-tional PET/CT:a self-control study
杨润君 1陈雪琪 1余浩军 1胡鹏程 1石洪成1
作者信息
- 1. 复旦大学附属中山医院核医学科、复旦大学核医学研究所、上海市影像医学研究所,上海 200032
- 折叠
摘要
目的 探讨全身PET/CT(TB PET/CT)1 min采集图像质量能否满足临床诊断需求.方法 回顾性分析2019年5月至2021年9月间复旦大学附属中山医院病理证实的90例肿瘤患者(男60例、女30例,年龄31～86岁)PET/CT影像资料.注射18F-FDG后,患者按照顺序随机原则先后完成TB PET/CT 1 min采集及常规PET/CT(C PET/CT)常规图像采集,采用配对样本t检验或Wilcoxon符号秩检验比较不同PET/CT采集所获得的图像质量.结果 C PET/CT 1 min采集与TB PET/CT 1 min采集的病灶 SUVmax分别为 12.5(5.8,16.6)和 15.9(7.9,24.6)(z=8.14,P＜0.001),纵隔血池、肝脏、肌肉的信噪比(SNR)分别为 6.2±1.7、9.4(7.7,11.8)、6.0(4.9,7.1)与 9.3±3.0、11.4(9.5,14.2)、8.3(7.3,10.1),肿瘤-血池比(TBR)、肿瘤-肝脏比(TLR)、肿瘤-肌肉比(TMR)分别为8.5(4.3,11.1)、6.1(2.9,7.7)、18.3(9.6,26.6)和 9.3(4.3,14.8)、6.7(3.0,10.4)、23.2(11.5,38.0),差异均有统计学意义(t=9.36,2值:4.44～7.40,均P＜0.001).结论 TB PET/CT 1 min采集的图像质量能够满足诊断需求,且优于C PET/CT常规采集的图像.
Abstract
Objective To investigate whether the image quality of total-body PET/CT(TB PET/CT)with 1 min acquisition can meet the clinical diagnostic requirements.Methods From May 2019 to September 2021,a total of 90 malignant tumor patients(60 males,30 females,age 31-86 years)with pri-mary lesions confirmed by pathological diagnosis in Zhongshan Hospital,Fudan University were respectively analyzed.All patients underwent conventional PET/CT(C PET/CT)scan with conventional clinical acqui-sition and TB PET/CT scan with 1 min acquisition after injecting 18F-FDG in random order.Paired t test or Wilcoxon signed rank test was used to analyze the image quality of these two scans.Results SUVmax of pri-mary lesions in TB PET/CT group was significantly higher than that in C PET/CT group(15.9(7.9,24.6)vs 12.5(5.8,16.6);z=8.14,P＜0.001),so were signal-to-noise ratio(SNR)of the blood pool,liver,mus-cles(9.3±3.0,11.4(9.5,14.2),8.3(7.3,10.1)vs6.2±1.7,9.4(7.7,11.8),6.0(4.9,7.1)),tumor-to-blood pool ratio(TBR)(9.3(4.3,14.8)vs 8.5(4.3,11.1)),tumor-to-liver ratio(TLR)(6.7(3.0,10.4)vs 6.1(2.9,7.7)),tumor-to-muscle ratio(TMR)(23.2(11.5,38.0)vs 18.3(9.6,26.6);t=9.36,z values:4.44-7.40,all P＜0.001).Conclusion The image quality of TB PET/CT scan with 1 min acquisition can meet the diagnostic requirements,and is better than the C PET/CT image quality with conventional clinical acquisition.
关键词
图像处理,计算机辅助/时间因素/正电子发射断层显像术/体层摄影术,X线计算机/氟脱氧葡萄糖F18Key words
Image processing,computer-assisted/Time factors/Positron-emission tomography/Tomography,X-ray computed/Fluorodeoxyglucose F18引用本文复制引用
基金项目
上海市临床重点专科建设项目(shslczdzk03401)
促进市市级医院临床技能与临床创新能力三年行动计划(SHDC2020CR3079B)
出版年
2024
NETL
NSTL
维普
万方数据