Fibroblast activation protein inhibitor(FAPI)has been the focus of nuclear medicine since its introduction.With the in-depth study of FAPI tracer,its clinical application in various non-malig-nant diseases has also been gradually reported.Many studies have confirmed its uptake in a variety of non-malignant diseases,which indicate that FAPI tracers have good application prospects.This article reviews the latest research status and clinical application of radiolabeled FAPIs in cardiovascular diseases,rheumat-ic immune diseases,immunoglobulin(Ig)G4-related diseases,renal fibrosis and other non-malignant disea-ses at home and abroad.
Antagonists and inhibitorsMembrane proteinsFibroblastsTrends