Thyroid cancer is one of the most common tumors of the endocrine system,characterized by high morbidity and low mortality.Thyroid stimulating hormone(TSH)is an important factor in the develop-ment of thyroid cancer.TSH suppression therapy is widely used in clinical practice to reduce recurrence and metastasis through long-term strict monitoring and control of postoperative TSH level in patients with differ-entiated thyroid cancer(DTC).However,the specific mechanism of the effect played by TSH in the prolif-eration and progression of DTC has not been clarified.The current researches focus on classifying the relation between TSH and the onset risk,adverse clinicopathological factors and prognosis of DTC,and the applica-ble scope of TSH suppression therapy and targeted TSH receptor(TSHR)therapy.This article reviews the relation between TSH and DTC and the latest research progress of TSH suppression therapy and TSHR targe-ted therapy.
维普
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