125I粒子近距离照射在口腔颌面部恶性肿瘤治疗中的临床应用进展
Progress in clinical application of125I seeds brachytherapy in the treatment of oral and maxillofacial malignant tumors
魏婷 1倪前伟 2杨自更 3黄孝泳 1孙海涛 4孙睿哲 1马超 5蔡冰冰 3高瞻2
作者信息
- 1. 新疆医科大学研究生院,乌鲁木齐 830054
- 2. 新疆军区总医院颌面外科,乌鲁木齐 830000
- 3. 新疆军区总医院核医学科,乌鲁木齐 830000
- 4. 北京大学第三医院肿瘤放疗科,北京 100191
- 5. 新疆军区总医院医学影像科,乌鲁木齐 830000
- 折叠
摘要
口腔颌面部恶性肿瘤威胁患者生命健康,严重影响患者的吞咽、语言功能和面容.其治疗方法中,125I粒子近距离照射治疗技术因手术创伤小,靶区组织剂量大分布均匀,对周边正常组织损伤小,可以减少医护人员辐射暴露等优点,受到广泛关注.利用125I粒子对口腔颌面部肿瘤进行持续、低剂量的近距离照射治疗,可以有效减小肿瘤体积,延长患者的生存期,治疗效果显著.该文针对125I粒子近距离照射在口腔颌面部恶性肿瘤的临床应用展开综述.
Abstract
Oral and maxillofacial malignant tumors threaten the life and health of patients,and seri-ously affect their swallowing,language function and face.125I seeds brachytherapy for oral and maxillofacial malignant tumors has been widely concerned and studied because of its advantages such as less surgical trauma,large and uniform dose distribution in the target tissue,little damage to the surrounding normal tissue,and reducing radiation exposure of medical staff.Low-dose brachytherapy with 125I seeds can effectively reduce the tumor volume and prolong the survival time of patients.This article reviews the clinical application of 125I seeds brachytherapy in oral and maxillofacial malignant tumors.
关键词
口腔肿瘤/近距离放射疗法/碘放射性同位素/发展趋势Key words
Mouth neoplasms/Brachytherapy/Iodine radioisotopes/Trends引用本文复制引用
基金项目
中华口腔医学会西部口腔医学临床科研基金(CSA-W2020-06)
出版年
2024
NETL
NSTL
万方数据