The excessive inflammatory response after acute myocardial infarction(AMI)is detri-mental to the repair of the infarcted myocardium,and anti-inflammatory interventions at the peak of inflam-mation have shown efficacy.Therefore,longitudinal monitoring of myocardial inflammatory evolution after AMI in vivo is important for individualized risk prediction,anti-inflammatory treatment strategies guidance and further prognosis improvement.68Ga-pentixafor,a promising novel probe targeting C-X-C chemokine re-ceptor 4(CXCR4)on the surface of inflammatory cells,with no special preparation before imaging,allows in vivo visualization of the inflammation intensity,extent and evolution in the infarcted myocardium as well as the response of other related extra-cardiac organs.This review referred to its radiopharmaceutical charac-teristics,research status,explorations and limitations in AMI.
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