摘要
心血管系统分枝杆菌感染十分少见,而有详细病理信息的报道较少.本文报道了 1例罕见的无症状心肌分枝杆菌感染尸检病例,患者死于术后肺动脉血栓栓塞,在尸检中偶然发现心肌分枝杆菌感染病灶,推测为心肌结核可能性较大,但死后心脏与肺脏石蜡组织结核分枝杆菌实时荧光定量PCR检测为阴性.另外,本文对分枝杆菌感染(重点对心肌结核)的好发人群、播散途径、临床表现、与心血管意外事件的关联以及诊疗进行讨论,以期提高临床医生对心肌分枝杆菌感染的认识.
Abstract
Mycobacterial infections of the cardiovascular system are rare and only a few reports provide detailed pathological information.This report presented a rare case of asymptomatic myocardial mycobacterial infection identified at autopsy.The patient died from pulmonary thromboembolism.The Myocardial mycobacterial lesions were found during the histological examination.Although myocardial tuberculosis was considered highly probable,real-time quantitative fluorescence PCR tests for Mycobacterium tuberculosis on paraffin-embedded heart and lung tissues were negative.This report discusses the predisposed populations,routes of dissemination,clinical manifestations,associations with cardiovascular events,and diagnosis and treatment of mycobacterium infections,with a focus on myocardial tuberculosis,to enhance clinicians'understanding of myocardial mvcobacterium infections.
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