Colorectal cancer is a kind of common tumor of the digestive system,which held the second place of morbidity and the forth place of mortality among the whole cancer types in China.Recent colorectal cancer's definite diagnosis method is tissue biopsy,which maintains disadvantages as invasiveness,relatively needs of technology and short on repeatability.Liquid biopsy is a new diagnose technology that diagnose cancer by body fluids(mainly peripheral blood),with advantages as high sensitivity,high compliance and noninvasiveness.Recently,liquid biopsy is mainly applied on early screening,companion diagnostics,drug selection and prognosis predication.Recently,liquid biopsy has achieved breakthrough progress on minimal residual disease(MRD)diagnosis.This article aims to conclude the effect of liquid biopsy on early screening,companion diagnostics,drug selection and prognosis predication of colorectal cancer.
关键词
结直肠肿瘤/液体活检/精准诊疗
Key words
Colorectal neoplasms/Liquid biopsy/Precision medicine