Objective In colorectal surgery,performing laparoscopic purse-string suture has always been a technical challenge,especially in natural orifice specimen extraction surgery(NOSES).Additionally,the formation of the"dangerous triangle area"at the colonic-rectal anastomosis site is a major factor contributing to anastomotic leakage.The clinical application of endoscopic linear-cutting purse-string stapler can effectively address these technical challenges.Methods This study included 5 patients with colorectal cancer who underwent radical surgery,including 4 cases of rectal cancer and 1 case of sigmoid colon cancer.In all patients,the process of colonic anastomosis and stapler fixation of the anvil during digestive tract reconstruction utilized endoscopic linear-cutting purse-string stapler.Results The average age of the patients was(54.4±8.6)years,and the average BMI was(24.7±2.9)kg/m2.Four patients underwent laparoscopic radical rectal cancer surgery with ileostomy,while one patient underwent NOSES Ⅳ.The average operation time was(123.60±15.37)minutes,the average intraoperative blood loss was(98±36)mL,and the average postoperative hospital stay was(9.4±0.5)days.No perioperative complications occurred in any of the patients.Conclusion The endoscopic linear-cutting purse-string stapler reduces the difficulty of digestive tract reconstruction in total laparoscopic sigmoid colon and rectal surgery.Its clinical application has significant value and potential for promotion,whether in routine laparoscopic surgery or NOSES.