As crucial proteins in sensing mechanical stress, mechanosensitive (MS) ion channels could transform external mechanical stimuli into electrochemical signals, enabling ion transmembrane movement. This movement signals the intracellular regulation of target genes. While various MS ion channels are present in odontogenic cell membranes, their roles in the cellular regulation and the exact mechanisms are still not fully understood. This review focused on the classification, expression, and functionality of MS ion channels in odontogenic cells.
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