Analysis of etiology of isolated microscopic hematuria in children
Objective:To explore the etiology of childhood isolated microscopic hematuria in China.Methods:Children with isolated microscopic hematuria diagnosed at our hospital from January 2014 to December 2018 were studied retrospectively to summary their clinical characteristics and final diagnosis.Results:There were 320 cases of isolated microscopic hematuria. The major (86.25%, 276/320) causes were glomerular diseases, including thin basement membrane nephropathy, purpura nephritis, post-infectious glomerulonephritis and Alport syndrome, while the minor (13.75%, 44/320) causes were non-glomerular diseases, including hypercalciuria or renalcalculus, left renal vein entrapment syndrome, febrile or exercise hematuria, and autoimmune disease. Thin basement membrane nephropathy is the most common cause (62.19%).Conclusion:Thin basement membrane nephropathy is the main cause of childhood isolated microscopic hematuria in China. The overall prognosis is good. Long-term follow-up and surveillance are more important and necessary than excessive examinations and treatments.
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