Progress in research of intestinal Behcet's disease
Intestinal Behcet's disease is a special subtype of Behcet's disease that involves the gastrointestinal tract and is characterized by gastrointestinal symptoms caused by intestinal ulcer lesions. At present, there is still a lack of objective tools and any single specific biomarker to assess disease activity. The diagnosis, differential diagnosis, and prognosis assessment are mainly based on endoscopy, biopsy, and CT scanning. Corticosteroids and aminosalicylic acid preparations are still the first-line and standard treatment options. For corticosteroid-dependent patients, immunosuppressants or tumor necrosis factor (TNF) inhibitors (TNF-i) can be used in combination. Strict surgical indications are required during the treatment process, but when severe and life-threatening complications that cannot be controlled by conservative treatments Occur, surgical treatment is required. This article reviews the predisposing factors and pathogenesis, clinical features, common complications and comorbidities, differential diagnosis, auxiliary examinations (laboratory, colonoscopic, and imaging), histopathological features, treatment, and prognosis of Behcet's disease, with an aim to provide some reference for clinicians.
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