Progress in reearch of action of mechanism of metformin
Metformin is currently the most commonly used oral hypoglycemic drug in the world. As research continues on this drug, metformin has been found to have a number of other potential benefits. Metformin can not only be used to lower blood sugar via multiple mechanisms, but it can also alter the intestinal flora and its metabolites, exert anti-inflammatory and anti-cancer effects, improve cardiovascular disease and Alzheimer's disease (AD), promote weight loss, treat polycystic ovary syndrome, and so on. With the emergence of more and more high-quality research evidence, it will be more widely used in clinics. In this paper, we review the current progress in the research of metformin, and discuss its common side effects and potential action of mechanism, with an aim to provide reference for clinical workers and researchers.