Analysis of factors influencing nosocomial infection with multi-drug resistant bacteria in intensive care unit of a tertiary hospital
Objective:To analyze factors influencing hospital infection with multiple drug-resistant organisms (MDRO) in the intensive care unit (ICU) of a tertiary hospital, so as to provide reference for the development of antecedent prevention and control strategies.Methods:The clinical data of 227 patients with MDRO infection admitted to the ICU of Shougang Hospital to Peking Univirsity from January 2019 to December 2022 were analyzed retrospectively. According to their drug sensitivity results, clinical data, and whether hospital infection occurred, the patients were divided into either a hospital infection group (114 cases) or a non-hospital infection group (113 cases). Pearson chi-square test, binary Logistic regression analysis, and multi-factor hierarchical analysis were applied to analyze the factors influencing MDRO infection in the ICU and summarize effective preventive measures.Results:Among 227 hospitalized patients with MDRO infection in the ICU in 2019—2022, days of ventilator use and types of antimicrobial drugs used were independent risk factors for hospital infection with MDRO in ICU patients, and surgery (postoperative) was an independent protective factor. The result was not influenced by patients' gender and age.Conclusion:For patients with hospital infection with MDRO in the ICU, targeted prevention, control, and intervention measures should be strengthened in clinical diagnosis and care according to the risk factors related to hospital infection to reduce the occurrence of hospital MDRO infection in the ICU.
万方数据
